导师信息

潘浩波

博士

研究员

邮箱 : hb.pan@siat.ac.cn

简介:

潘浩波，博士，研究员，博士生导师，中国科学院深圳先进技术研究院医药所副所长，深圳理工大学药学院长聘科研杰出教授，国际先进材料协会会士（IAAM Fellow），国家级领军人才，科技部“十四五”重点研发计划重点专项首席科学家，人体组织与器官退行性研究中心主任，广东省生物医用材料国际联合研究中心主任，广东省海洋生物材料工程技术中心主任，深圳市海洋生物医用材料重点实验室主任，香港大学荣誉教授。兼任中国医疗保健促进会理事，骨科生物材料学部主任委员；中国生物材料学会理事，海洋生物材料分会侯任主任委员和生物陶瓷分会副主任委员等国内学术委员会职务。长期从事生物医用材料与转化研究，提出了碱性调控细胞稳态的科学观点，为新型再生材料的设计提供了重要理论基础。四度入选全球前2%顶尖科学家榜单。以第一完成人获得深圳市自然科学二等奖。先后发表论文200余篇，包括通讯作者论文Progress in Materials Science, Advanced Materials, Advanced Functional Materials, Nature Communications, Chemical Engineering Journal, Advanced Science, Bioactive Materials, ACS Applied Materials Interface等，SCI他引10000余次，H指数62。参与编辑两部教育部生物医用材料丛书，担任《海洋生物材料》副主编和《生物复合材料》编委。孵化科技成果转化企业三家，取得了科技部重点研发计划项目，作为联合创始人，发起生物材料成果转化天使基金，已投资生物材料初创企业8家。2011年回国建立人体组织与器官退行性研究中心，促进了中心的不断发展与壮大，中心目前拥有国家级人才4人，中科院青年促进会5人，全球前2%顶尖科学家6人，正高职称9人，已建设成为国内生物材料领域一支重要的力量。

个人主页: https://people.ucas.edu.cn/~panhaobo

研究方向:

生物医用材料、骨再生医学、3D 生物打印、材料生物学效应、细胞生物学

主要学术任职:

中国医疗保健促进会理事，骨科生物材料学部主任委员；中国生物材料学会理事，海洋生物材料分会候任主任委员，生物陶瓷分会副主任委员；广东省生物医用材料国际联合研究中心主任；广东省海洋生物材料工程技术中心主任；深圳市海洋生物医药材料重点实验室主任；中国康复医学会修复重建外科专业委员会医学转化组副主任委员；中国生物材料学会烧伤创面修复材料分会第一届委员会常务委员

主要代表论著（通讯或一作，最具代表性 5 篇）:

(1) Jua Kim, Haobo Pan*. Effects of Magnesium Alloy Corrosion on Biological Response- Perspectives of Metal-Cell Interaction. Progress in Materials Science. 2023;133:101039 (IF:48.165)

(2) Shaoquan Bian, Liuzhi Hao, Xin Qiu, Jun Wu, Hao Chang, Guan-Ming Kuang, Sheng Zhang, Xiaohua Hu, Yakang Dai, Zhiyong Zhou, Fangli Huang, Chun Liu, Xuenong Zou, Wenguang Liu, Willima W. Lu, Haobo Pan*, Xiaoli Zhao*. An Injectable Rapid-Adhesion and Anti-Swelling Adhesive Hydrogel for Hemostasis and Wound Sealing. Advanced Functional Materials 2022;32: 2207741 (IF: 19.924)

(3) Shuaijie Li, Liyan Zhang, Chunyu Liu, Jua Kim, Kun Su, Tingli Chen, Limin Zhao, Xiaomei Lu, Hao Zhang, Yinglin Cui, Xu Cui*, Feng Yuan*, Haobo Pan*. Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects. Bioactive Materials 2023;23:101-117 (IF=16.874)

(4) Pang, Libin; Zhao, Renliang; Chen, Jing; Ding, Jingxin; Chen, Xiaochen; Chai, Wenwen; Cui, Xu; Li, Xiaolin*; Wang, Deping*; Pan, Haobo*. Osteogenic and anti-tumor Cu and Mn-doped borosilicate nanoparticles for syncretic bone repair and chemodynamic therapy in bone tumor treatment. Bioactive Materials. 2022;12:1-15 (IF:16.874)

(5) Hao Zhang; Yinglin Cui; Xianglong Zhuo; Jua Kim; Honglong Li; Shuaijie Li; Hongsheng Yang; Kun Su; Chunyu Liu; Pengfei Tian; Xian Li; Li Li; Deping Wang; Limin Zhao; Jianyun Wang; Xu Cui*; Bing Li*; and Haobo Pan*. Biological Fixation of Bioactive Bone Cement in Vertebroplasty: The First Clinical Investigation of Borosilicate Glass (BSG) Reinforced PMMA Bone Cement. ACS Applied Materials & Interfaces. 202223;14(46):51711-51727 (IF:10.383)

(6) Tao Liang; Huanhuan Zhang; Haobo Pan*; Ying Zhao*. Insight into microbiologically induced corrosion performance of magnesium in tryptic soy broth with S. aureus and E. coli. Journal of Materials Science & Technology. 2022;115: 221-231 (IF: 10.319) (7) Yang, Minggang; Qiu, Shi; Coy, Emerson; Li, Shuaijie; Zaleski, Karol; Zhang, Yao*; Pan, Haobo*; Wang, Guocheng*. NIR-responsive TiO2 Biometasurface: Towards in situ Photodynamic Antibacterial Therapy for Biomedical Implants. Advanced Materials. 2022;34:e2106314 (IF: 32.086)

(8) Yongkang Huang, Xinyun Zhai*, Tengfei Ma, Mengzhen Zhang, Houzhi Yang, Shuai Zhang, Junbo Wang, Wenguang Liu, Xin Jin, William Weijia Lu, Xiaoli Zhao, Weiyu Hou, Tianwei Sun, Jie Shen, Haobo Pan*, Yaping Du*, Chun-Hua Yan. A Unified Therapeutic–Prophylactic Tissue-Engineering Scaffold Demonstrated to Prevent Tumor Recurrence and Overcoming Infection toward Bone Remodeling. Advanced Materials. 2023;doi/10.1002/adma.202300313 (IF: 32.086)

(9) Pang, Libin; Tian, Pengfei; Cui, Xu; Wu, Xiuping; Zhao, Xiaoli; Wang, Hui; Wang, Deping*; Pan, Haobo*. In Situ Photo-Cross-Linking Hydrogel Accelerates Diabetic Wound Healingthrough Restored Hypoxia-Inducible Factor 1-Alpha Pathway and Regulated Inflammation. ACS Applied Materials & Interfaces. 2021;13(25): 29363-29379 (IF=10.383)

(10) Cui, Xu; Huang, Chengcheng; Chen, Zhizhen; Zhang, Meng; Liu, Chunyu; Su, Kun; Wang, Jianyun; Li, Li; Wang, Renxian; Li, Bing; Chen, Dafu; Ruan, Changshun; Wang, Deping; Lu, William W.; Pan, Haobo*. Hyaluronic acid facilitates bone repair effects of calcium phosphate cement by accelerating osteogenic expression. Bioactive Materials. 2021;6(11): 3801-3811 (IF: 16.874)

(11) Liang, Tao; Zeng, Lilan; Shi, Yunzhu; Pan, Haobo*; Chu, K. Paul; Yeung, W.K. Kelvin*; Zhao, Ying*. In vitro and in vivo antibacterial performance of Zr & O PIII magnesium alloys with high concentration of oxygen vacancies. Bioactive Materials. 2021;6(10):3049-3061 (IF: 16.874)

(12) Huawei Qu; Zhenyu Han; Zhigang Chen; Lan Tang; Chongjian Gao; Kaizheng Liu; Haobo Pan*; Hongya Fu*; Changshun Ruan*. Fractal design boosts extrusion-based 3D printing of bone-mimicking radial-gradient scaffolds. Research. 2021;9892689 (IF: 11.036)

(13)Zhai, Xinyun; Ruan, Changshun ; Ma, Yufei; Cheng Delin; Wu, Mingming; Liu, Wenguang; Zhao, Xiaoli; Pan, Haobo ; Lu, William Weijia ,3D-Bioprinted Osteoblast-Laden Nanocomposite Hydrogel Constructs with Induced Microenvironments Promote Cell Viability, Differentiation, and Osteogenesis both In Vitro and In Vivo, Advanced Science, 2018 , 5 (3) :1700550 IF:12.441*通讯作者

(14) Liu, Wenlong ; Wang, Ting ; Yang, Chun ; Darvell, Brian W.; Wu, Jun;Lin, Kaili; Chang, Jiang; Pan, Haobo ; Lu, William W. ,Alkaline biodegradable implants for osteoporotic bone defects—importance of microenvironment pH, Osteoporosis International, 2016.1, 27(1): 93~104 IF=3.445*通讯作者

(15) Liu, Wenlong; Dan, Xiuli; Wang, Ting; Lu, William W.; Pan, Haobo ,A Bone-Implant Interaction Mouse Model for Evaluating Molecular Mechanism of Biomaterials/Bone Interaction, TISSUE ENGINEERING: Part C, 2016.11.11, 22: 1018~1027 IF= 3.892 *通讯作者

(16) Ruan, Changshun; Hu, Nan; Ma, Yufei; Li, Yuxiao; Liu, Juan; Zhang,Xinzhou; Pan, Haobo ,The interfacial pH of acidic degradable polymeric biomaterials and its effects on osteoblast behavior , SCIENTIFIC REPORTS, 2017.7 IF= 4.259 *通讯作者

(17)Yuhui Shen, Waiching Liu, Chunyi Wen, Haobo Pan*, B.W. Darvell, Wenhai Huang, William W Lu, “Bone regeneration: importance of local pH - strontium -doped borosilicate scaffold” J Mater Chem 2012; 22: 8662-8670 IF: 5.968 *通讯作者