导师信息
-
刘开政
博士
副研究员
邮箱 : kz.liu@siat.ac.cn
简介:
中国科学院深圳先进技术研究院副研究员,硕士生导师。欧盟玛丽居里学者,比利时鲁汶大学博士后,欧洲分子生物学会(EMBO)短期基金获得者。分别在南开大学、英国伦敦大学学院和荷兰奈梅亨大学取得学士、硕士和博士学位。与欧洲科研机构合作,致力于3D微环境中的细胞生物力学研究以及新型非线性人工聚合物材料-螺旋聚异腈(PIC)水凝胶的研发、生产与生物医学应用。在Cell Reports Physical Science、The Proceedings of the National Academy of Sciences(PNAS)、Bioactive Materials、ACS Applied Materials & Interfaces和Biomacromolecules等国际高水平杂志发表论文十余篇。
个人主页: https://scholar.google.com/citations?user=FMq1F5IAAAAJ&hl=en
研究方向:
细胞-基质力学互作;生物流变学;螺旋聚异腈(PIC)水凝胶的生物医学应用
主要学术任职:
Smart Materials in Medicine、Frontiers in Bioengineering、ACS Pharmacology & Translational Science与ACS Applied Materials & Interfaces期刊独立审稿人。
主要代表论著(通讯或一作,最具代表性 5 篇):
Liu, K. #, Vandaele, J. #, Yuan, H., Blank, K. G., Hammink, R., Kouwer, P. H., & Rocha, S. (2024). Structure and applications of PIC-based polymers and hydrogels. Cell Reports Physical Science, 5(2), 101834. (IF=8.9,第一作者)
Yuan, H. #, Liu, K. #, Cóndor, M., Barrasa-Fano, J., Louis, B., Vandaele, J., ... & Rocha, S. (2023). Synthetic fibrous hydrogels as a platform to decipher cell–matrix mechanical interactions. Proceedings of the National Academy of Sciences, 120(15), e2216934120. (IF=11.1,共同第一作者)
Liu, K., Wiendels, M., Yuan, H., Ruan, C., & Kouwer, P. H. (2022). Cell-matrix reciprocity in 3D culture models with nonlinear elasticity. Bioactive materials, 9, 316-331. (IF=18.9,第一作者,ESI高被引论文)
Liu, K., Veenendaal, T., Wiendels, M., Ruiz-Zapata, A. M., van Laar, J., Kyranas, R., Enting, H., van Cranenbroek, B., Koenen, H., Mihaila, S., Oosterwijk, E., Kouwer, P.H. (2020) Synthetic extracellular matrices as a toolbox to tune stem cell secretome. ACS applied materials & interfaces,12(51), 56723-56730. (IF=9.5,第一作者)
Liu, K., Mihaila, S. M., Rowan, A., Oosterwijk, E., & Kouwer, P. H. (2019). Synthetic extracellular matrices with nonlinear elasticity regulate cellular organization. Biomacromolecules, 20(2), 826-834. (IF=6.2,第一作者)
Ma, C.#, Liu, K.#, Li, Q., Xiong, Y., Xu, C., Zhang, W., Ruan C., Li X., & Lei, X. (2022). Synthetic Extracellular Matrices for 3D Culture of Schwann Cells, Hepatocytes, and HUVECs. Bioengineering, 9(9), 453. (IF=4.6,共同第一作者)
Liu, K., Vandaele, J., Bernhagen, D., van Erp, M., Oosterwijk, E., Timmerman, P., ... & Kouwer, P. H. (2022). Rapid stem cell spreading induced by high affinity α5β1 integrin-selective bicyclic RGD peptide in biomimetic hydrogels. bioRxiv, 2022-02.