导师信息

• 

  赵晓丽

  博士

  研究员

  邮箱 : zhao.xl@siat.ac.cn

简介:

   中国科学院深圳先进技术研究院研究员，博导，深圳市高层次人才，广东省工程技术中心副主任，香港大学博士毕业， 美国约翰霍普金斯大学访问学者，研究领域为生物环境响应智能材料、可注射水凝胶与器械、纳米载体、组织工程支架、3d打印精准成型、纳米纤维构建等，科技部项目课题负责人，主持国自然项目累计3项，承担和参与国家和省市级科研项目20余项，相关研究已在Nature Communication, Adv Funct Mater, ACS Nano，Chemical Engineering Journal, Adv Sci，J. Nanobiotechnology等杂志上发表SCI检索文章50多篇，授权16项，转化1项，获得深圳市自然科学二等奖，在国际和国内会议上做报告40余次。

个人主页: http://htod.siat.ac.cn/index.php/Team/detail.shtml?id=10&cid=11

研究方向:

生物材料，可注射凝胶，药物递送，干细胞，组织再生，3D打印

主要学术任职:

国际矫形与创伤外科学会中国部骨科基础学会委员、

中国老年学和老年医学学会骨质疏松分化创新与转换专家委员会委员、

广东省基层医药学会创伤救治专委会会员、

中国生物材料学会会员

获奖及荣誉：

深圳市自然科学二等奖

深圳市高层次人才

学科类别：

1 化学与材料

2 细胞生物学

3 药学

 

主要代表论著（通讯或一作，最具代表性 5 篇）:

[1]  Bo Liu, Hui Li, Fengzhen Meng, Ziyang Xu, Liuzhi Hao, Yuan Yao, Hao Zhu, Chenmin Wang, Jun Wu, Shaoquan Bian, Willima W. Lu, Wenguang Liu,* Haobo Pan,* Xiaoli Zhao*.4D printed hydrogel scaffold with swelling-stiffening properties and programmable deformation for minimally invasive implantation , Nature Communication, 2024,15, 1587  (IF 1.6 Q1)

[2]  Hao Chang#, Pengfei Tian#, Liuzhi Hao#, Chengwei Hu, Bo Liu, Fengzhen Meng, Xin Yi, Xiaohua Pan, Xiaohua Hu, Huan Wang, Xinyun Zhai, Xu Cui, Jason Pui Yin Cheung, Xuanyong Liu, Haobo Pan*, Shaoquan Bian*, Xiaoli Zhao*, Antioxidative bioactive glass reinforced injectable hydrogel with reactive oxygen species scavenging capacity for diabetic wounds treatment, Chemical Engineering Journal, 2024,148768, (IF 15.1 Q1)

[3]  Liuzhi Hao, Shuwen Huang, Tongling Huang, Dan Yi, Chenmin Wang, Lixin Cheng , Min Guan, Jun Wu, Di Chen, Haobo Pan, William W. Lu, and Xiaoli Zhao*,Bone Targeting miR-26a Loaded Exosome-Mimetics for Bone Regeneration Therapy by Activating Wnt Signaling Pathway. Chemical Engineering Journal, 2023,471：144594 (IF 15.1 Q1) 

[4] Ke Lu, Qingyun Wang, Liuzhi Hao, Guizheng Wei, Tingyu Wang, William W. Lu, Guozhi Xiao, Liping Tong, Xiaoli Zhao*, Di Chen*. miR-204 ameliorates osteoarthritis pain by inhibiting SP1-LRP1 signaling and blocking neuro-cartilage interaction, Bioactive Materials,2023,26:425-436 (IF18.9, Q1)

[5]  Shaoquan Bian^#, Liuzhi Hao^#, Xin Qiu, Jun Wu, Hao Chang, Guan-ming Kuang, Sheng Zhang, Xiaohua Hu, Yakang Dai, Zhiyong Zhou, Fangli huang, Chun Liu, Xuenong Zou, Wenguang Liu, Willima W. Lu, Haobo Pan*, Xiaoli Zhao*. An injectable rapid-adhesion and anti-swelling adhesive hydrogel for hemostasis and wound sealing，Advanced Functional Materials,  Adv. Funct. Mater. 2022, 32, 2207741. (IF 19.924， Q1，Inside Cover)

[6]  Feiyang Li#, Jun Wu# , Daiye Li#, Liuzhi Hao#, Yanqun Li, Dan Yi, Kelvin W.K. Yeung, Di Chen, William W. Lu, Haobo Pan, Tak Man Wong*, and Xiaoli Zhao*. Engineering Stem Cells to Produce Exosomes with Enhanced Bone Regeneration Effects: An Alternative Strategy for Gene Therapy. Journal of Nanobiotechnology, 2022, 20:135 (IF 10.2，Q1, the article of the year award 1%)

[7]  Jing Wang#, Hao Xiong#, Tonghe Zhu, Yuan Liu, Haobo Pan, Cunyi Fan*, Xiaoli Zhao*, William Weijia Lu. Bioinspired Multichannel Nerve Guidance Conduit Based on Shape Memory Nanofibers for Potential Application in Peripheral Nerve Repair, ACS Nano，2020, 14, 12579−12595 (IF 17.1, Q1)

[8]  Yanqun Li, Jianhui Yue, Yuan Liu, Jun Wu, Min Guan, Di Chen, Haobo Pan**，Xiaoli Zhao*, William W. Lu. Strontium Regulates Stem Cell Fate during Osteogenic Differentiation through Asymmetric Cell Division. Acta Biomaterialia, 2021,119,432-443. (IF 9.7，Q1)

[9]  Zhiqiang Zheng#, Shaoquan Bian#, Zhiqiang Li, Zhiyang Zhang, Yuan Liu, Xinyun Zhai, Haobo Pan, Xiaoli Zhao*. Catechol modified quaternized chitosan enhanced wet adhesive and antibacterial properties of injectable thermo-sensitive hydrogel for wound healing. Carbohydrate Polymers 2020, 249,116826 (IF11.2, Q1)

[10]  Qingchang Chen#, Chuping Zheng# , Yanqun Li#, Shaoquan Bian, Haobo Pan, Xiaoli Zhao*, and William W. Lu. Bone Targeted Delivery of SDF1 via Alendronate Functionalized Nanoparticles in Guiding Stem Cell Migration. ACS Appl. Mater. Interfaces,2018, 10 (28), 23700–23710 （IF:9.5, Q1)