导师信息

潘浩波

博士

研究员

邮箱 : hb.pan@siat.ac.cn

简介:

潘浩波，博士，三级研究员，博士生导师，中国科学院深圳先进技术研究院医药所副所长，人体组织与器官退行性研究中心主任，国际先进材料协会会士（IAAM Fellow），广东省生物医用材料国际联合研究中心主任，广东省海洋生物材料工程技术中心主任，深圳市海洋生物医用材料重点实验室主任，十四五科技部重点研发计划首席科学家，香港大学荣誉教授，三度入选全球前2%顶尖科学家榜单。兼任中国医促会理事，骨科生物材料学部主任委员；中国生物材料学会理事，海洋生物材料分会主任委员，生物陶瓷分会副主任委员等国内9个学术委员会职务。长期从事骨科生物医用材料研究，提出了“碱性微环境可调控骨稳态”的科学观点，为新型骨科生物材料设计提供了重要理论基础。先后发表高水平论文180余篇，包括 Progress in Materials Science, Advanced Materials, Advanced Functional Materials, Advanced Science, Research, Bioactive Materials, ACS Applied Materials Interface, Acta Biomaterialia 等，SCI他引7000余次，单篇最高引用 342 次。参与编辑两部教育部生物医用材料丛书，担任《海洋生物材料》副主编和《生物复合材料》编委。孵化科技成果转化企业三家，取得了科技部生物材料与植入器械创新示范基地建设项目，作为联合创始人，发起生物材料成果转化天使基金，已投资生物材料初创企业8家。2011年回国建立人体组织与器官退行性研究中心，促进了中心的不断发展与壮大，中心目前拥有国家级人才4人，中科院青年促进会5人，全球前2%顶尖科学家6人，正高职称9人，已建设成为国内生物材料领域一支重要的力量。

个人主页: http://htod.siat.ac.cn/Team/detail.shtml?id=2&cid=11

研究方向:

生物医用材料、骨再生医学、3D 生物打印、材料生物学效应、细胞生物学

主要学术任职:

中国医疗保健促进会理事，骨科生物材料学部主任委员；中国生物材料学会理事，海洋生物材料分会候任主任委员，生物陶瓷分会副主任委员；广东省生物医用材料国际联合研究中心主任；广东省海洋生物材料工程技术中心主任；深圳市海洋生物医药材料重点实验室主任；中国康复医学会修复重建外科专业委员会医学转化组副主任委员；中国生物材料学会烧伤创面修复材料分会第一届委员会常务委员

主要代表论著（通讯或一作，最具代表性 5 篇）:

(1) Jua Kim, Haobo Pan*. Effects of Magnesium Alloy Corrosion on Biological Response- Perspectives of Metal-Cell Interaction. Progress in Materials Science. 2023;133:101039 (IF:48.165)

(2) Shaoquan Bian, Liuzhi Hao, Xin Qiu, Jun Wu, Hao Chang, Guan-Ming Kuang, Sheng Zhang, Xiaohua Hu, Yakang Dai, Zhiyong Zhou, Fangli Huang, Chun Liu, Xuenong Zou, Wenguang Liu, Willima W. Lu, Haobo Pan*, Xiaoli Zhao*. An Injectable Rapid-Adhesion and Anti-Swelling Adhesive Hydrogel for Hemostasis and Wound Sealing. Advanced Functional Materials 2022;32: 2207741 (IF: 19.924)

(3) Shuaijie Li, Liyan Zhang, Chunyu Liu, Jua Kim, Kun Su, Tingli Chen, Limin Zhao, Xiaomei Lu, Hao Zhang, Yinglin Cui, Xu Cui*, Feng Yuan*, Haobo Pan*. Spontaneous immunomodulation and regulation of angiogenesis and osteogenesis by Sr/Cu-borosilicate glass (BSG) bone cement to repair critical bone defects. Bioactive Materials 2023;23:101-117 (IF=16.874)

(4) Pang, Libin; Zhao, Renliang; Chen, Jing; Ding, Jingxin; Chen, Xiaochen; Chai, Wenwen; Cui, Xu; Li, Xiaolin*; Wang, Deping*; Pan, Haobo*. Osteogenic and anti-tumor Cu and Mn-doped borosilicate nanoparticles for syncretic bone repair and chemodynamic therapy in bone tumor treatment. Bioactive Materials. 2022;12:1-15 (IF:16.874)

(5) Hao Zhang; Yinglin Cui; Xianglong Zhuo; Jua Kim; Honglong Li; Shuaijie Li; Hongsheng Yang; Kun Su; Chunyu Liu; Pengfei Tian; Xian Li; Li Li; Deping Wang; Limin Zhao; Jianyun Wang; Xu Cui*; Bing Li*; and Haobo Pan*. Biological Fixation of Bioactive Bone Cement in Vertebroplasty: The First Clinical Investigation of Borosilicate Glass (BSG) Reinforced PMMA Bone Cement. ACS Applied Materials & Interfaces. 202223;14(46):51711-51727 (IF:10.383)

(6) Tao Liang; Huanhuan Zhang; Haobo Pan*; Ying Zhao*. Insight into microbiologically induced corrosion performance of magnesium in tryptic soy broth with S. aureus and E. coli. Journal of Materials Science & Technology. 2022;115: 221-231 (IF: 10.319) (7) Yang, Minggang; Qiu, Shi; Coy, Emerson; Li, Shuaijie; Zaleski, Karol; Zhang, Yao*; Pan, Haobo*; Wang, Guocheng*. NIR-responsive TiO2 Biometasurface: Towards in situ Photodynamic Antibacterial Therapy for Biomedical Implants. Advanced Materials. 2022;34:e2106314 (IF: 32.086)

(8) Yongkang Huang, Xinyun Zhai*, Tengfei Ma, Mengzhen Zhang, Houzhi Yang, Shuai Zhang, Junbo Wang, Wenguang Liu, Xin Jin, William Weijia Lu, Xiaoli Zhao, Weiyu Hou, Tianwei Sun, Jie Shen, Haobo Pan*, Yaping Du*, Chun-Hua Yan. A Unified Therapeutic–Prophylactic Tissue-Engineering Scaffold Demonstrated to Prevent Tumor Recurrence and Overcoming Infection toward Bone Remodeling. Advanced Materials. 2023;doi/10.1002/adma.202300313 (IF: 32.086)

(9) Pang, Libin; Tian, Pengfei; Cui, Xu; Wu, Xiuping; Zhao, Xiaoli; Wang, Hui; Wang, Deping*; Pan, Haobo*. In Situ Photo-Cross-Linking Hydrogel Accelerates Diabetic Wound Healingthrough Restored Hypoxia-Inducible Factor 1-Alpha Pathway and Regulated Inflammation. ACS Applied Materials & Interfaces. 2021;13(25): 29363-29379 (IF=10.383)

(10) Cui, Xu; Huang, Chengcheng; Chen, Zhizhen; Zhang, Meng; Liu, Chunyu; Su, Kun; Wang, Jianyun; Li, Li; Wang, Renxian; Li, Bing; Chen, Dafu; Ruan, Changshun; Wang, Deping; Lu, William W.; Pan, Haobo*. Hyaluronic acid facilitates bone repair effects of calcium phosphate cement by accelerating osteogenic expression. Bioactive Materials. 2021;6(11): 3801-3811 (IF: 16.874)

(11) Liang, Tao; Zeng, Lilan; Shi, Yunzhu; Pan, Haobo*; Chu, K. Paul; Yeung, W.K. Kelvin*; Zhao, Ying*. In vitro and in vivo antibacterial performance of Zr & O PIII magnesium alloys with high concentration of oxygen vacancies. Bioactive Materials. 2021;6(10):3049-3061 (IF: 16.874)

(12) Huawei Qu; Zhenyu Han; Zhigang Chen; Lan Tang; Chongjian Gao; Kaizheng Liu; Haobo Pan*; Hongya Fu*; Changshun Ruan*. Fractal design boosts extrusion-based 3D printing of bone-mimicking radial-gradient scaffolds. Research. 2021;9892689 (IF: 11.036)

(13)Zhai, Xinyun; Ruan, Changshun ; Ma, Yufei; Cheng Delin; Wu, Mingming; Liu, Wenguang; Zhao, Xiaoli; Pan, Haobo ; Lu, William Weijia ,3D-Bioprinted Osteoblast-Laden Nanocomposite Hydrogel Constructs with Induced Microenvironments Promote Cell Viability, Differentiation, and Osteogenesis both In Vitro and In Vivo, Advanced Science, 2018 , 5 (3) :1700550 IF:12.441*通讯作者

(14) Liu, Wenlong ; Wang, Ting ; Yang, Chun ; Darvell, Brian W.; Wu, Jun;Lin, Kaili; Chang, Jiang; Pan, Haobo ; Lu, William W. ,Alkaline biodegradable implants for osteoporotic bone defects—importance of microenvironment pH, Osteoporosis International, 2016.1, 27(1): 93~104 IF=3.445*通讯作者

(15) Liu, Wenlong; Dan, Xiuli; Wang, Ting; Lu, William W.; Pan, Haobo ,A Bone-Implant Interaction Mouse Model for Evaluating Molecular Mechanism of Biomaterials/Bone Interaction, TISSUE ENGINEERING: Part C, 2016.11.11, 22: 1018~1027 IF= 3.892 *通讯作者

(16) Ruan, Changshun; Hu, Nan; Ma, Yufei; Li, Yuxiao; Liu, Juan; Zhang,Xinzhou; Pan, Haobo ,The interfacial pH of acidic degradable polymeric biomaterials and its effects on osteoblast behavior , SCIENTIFIC REPORTS, 2017.7 IF= 4.259 *通讯作者

(17)Yuhui Shen, Waiching Liu, Chunyi Wen, Haobo Pan*, B.W. Darvell, Wenhai Huang, William W Lu, “Bone regeneration: importance of local pH - strontium -doped borosilicate scaffold” J Mater Chem 2012; 22: 8662-8670 IF: 5.968 *通讯作者